Insulin Resistance (HOMA-IR) Calculator

How to calculate HOMA-IR?

The Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) is a widely used method that assesses the balance between hepatic glucose output and insulin secretion. It provides a snapshot of how efficiently your body uses insulin to manage blood sugar levels, specifically by comparing fasting levels of both glucose and insulin.

HOMA-IR = (Glucose [mg/dL] × Insulin [μIU/mL]) / 405

Using the Insulin Resistance calculator: an example

To better understand the calculation, consider an individual with a fasting Blood Glucose of 90 mg/dL and a fasting Insulin level of 6 μIU/mL.

Step-by-step calculation:

• Multiplication: Multiply 90 by 6 to get 540.
• Division: Divide the product (540) by the constant 405.
• Result: This results in a HOMA-IR of 1.33, which is generally considered within the normal range.

Medical Disclaimer

This tool is intended for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding clinical interpretations of your lab results.

Frequently Asked Questions

What is a good HOMA-IR score?
A score below 1.0 is considered optimal insulin sensitivity. Scores between 1.0 and 1.9 are typically viewed as normal, while higher scores may indicate increasing resistance.

When should I test?
Testing must be done in a fasted state, usually after 8 to 12 hours of no caloric intake. This ensures the glucose and insulin levels reflect your baseline metabolism.

Is this a diagnosis?
No, this calculation is a marker used by clinicians. A formal diagnosis of insulin resistance or metabolic syndrome requires a full clinical evaluation and history.