Adjust the QT interval for heart rate to assess the risk of arrhythmias and long QT syndrome.
Bazett's Formula:
432 ms
Fridericia's Formula:
421 ms
Framingham's Formula:
422 ms
Normal QTc is typically below 440ms for men and 460ms for women.
The QT interval varies with heart rate; QTc normalizes this value to a heart rate of 60 bpm for standard clinical assessment.
Formula (Bazett): QTc = QT / √RR where RR is the interval between heartbeats in seconds.
QTc = QT / √RR
Consider a patient with a QT Interval of 400ms and a Heart Rate of 75 bpm.
A prolonged QTc interval is a biomarker for ventricular tachyarrhythmias like Torsades de Pointes and is used to monitor drug safety.
Bazett is most common but tends to over-correct at high heart rates; Fridericia or Framingham are often preferred for tachycardia.
Generally, QTc > 470ms in men and > 480ms in women is considered definitely prolonged.
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